Dr. Antzelevitch is the Executive Director and Director of Research of the Masonic Medical Research Laboratory (MMRL), an internationally prominent biomedical research institute located in Utica, NY. He also holds an academic appointment as Professor of Pharmacology at the SUNY Health Science Center at Syracuse and an endowed chair in Experimental Cardiology (Gordon K. Moe Scholar) at the MMRL. Dr. Antzelevitch succeeded Dr. Gordon K. Moe, who served as Director of the institute from 1959 to 1984.

Dr. Antzelevitch’s career has been highlighted by a number of awards and honors. Recent awards and honors include the Distinguished Service Award of the RAM Medical Research Foundation, the Charles Henry Johnson Medal and the Distinguished Achievement Medal of the Grand Lodge of Masons of NYS, Distinguished Scientist Award, North American Society of Pacing and Electrophysiology (NASPE), Excellence in Cardiovascular Science Award of the NE Affiliate American Heart Association. He was elected a Fellow of the American College of Cardiology in 1996 and is listed in nearly a dozen Who’s Who and International Directories of distinguished leaders and men of science. From 1996 to 1998 he served as President of the International Cardiac Electrophysiology Society, a society of basic and clinical scientists and physicians from countries throughout the world specializing in cardiac electrophysiology and arrhythmias. He currently serves as Secretary/Treasurer of the Society. In addition, he has received several other Masonic and Civic awards and was recently elected as a Fellow of the Heart Rhythm Society. Dr. Antzelevitch was selected to be the recipient of the 2007 Carl J. Wiggers Award of the American Physiological Society. .

His contributions to the scientific literature include over 310 original papers and book chapters, over 250 abstracts, four books. He is an internationally renowned authority in these areas and is an often invited to speak at international symposia and to present seminars and Cardiology Grand Rounds at medical schools and institutes throughout the world. His scientific achievements include 1) the discovery and characterization of reflected reentry and phase 2 reentry as mechanisms of extrasystolic activity capable of precipitating life–threatening ventricular tachycardia and fibrillation; 2) demonstration of electrical heterogeneity within ventricular myocardium, which has opened a new door to our understanding of electrophysiology and pharmacology of the heart and mechanisms of arrhythmogenesis; 3) delineation of the cellular and ionic basis for the long QT, Brugada, and short QT syndromes as well as catecholaminergic VT; and 4) the cellular and ionic basis fore the J wave and T wave of the ECG.

His contribution to the training of promising young scientists and physicians is evidenced by his students' first place or finalist standing in eight international Young Investigator Award competitions at the American College of Cardiology, the North American Society for Pacing and Electrophysiology and the International Society for Computerized Electrocardiography.

Dr. Antzelevitch is a member of and has served as Chairman of a number of committees at the National Institutes of Health, the American Heart Association (AHA) and the Heart Rhythm Society (HRS). Dr. Antzelevitch serves on Editorial Board of several leading medical journals.