Research Scientist – Molecular Genetics and Experimental Cardiology

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Research Interests

  • Translational and clinical cardiology, specifically in the area of cardiomyopathy, electrophysiology and arrhythmia, such as inherited sudden cardiac death syndromes.
  • Cardiac electrobiology, epidemiology, risk stratification, and treatment of heart failure, arrhythmia, myocardial infarction, and sudden cardiac death, et al.
  • Drug development and therapy. Cardiac pharmacology in animal model, stem cell model, cell lines, and patients.
  • Molecular genetics and mutation analysis of the basis for cardiac arrhythmias and sudden cardiac death.
  • Molecular and cellular characteristics of action potential and ion channels in heart, and the characteristics and underlying mechanism of ECG markers, such as J wave, T wave, U wave and QT interval, and possible therapy.
  • Gene expression and modulation in human and animal models with cardiac arrhythmias.
  • Stem cells and iPSC cells.

Professional Memberships

  • Member of CSPE (Chinese Society of Cardiac Pacing and Electrophysiology)
  • Member of APS (the America Physiological Society)
  • Member of CES (Cardiac Electrophysiology Society)
  • Lifetime Member of CnAHA (Chinese American Heart Association)
  • Fellow of HRS, FHRS (Heart Rhythm Society)
  • Fellow of AHA, FAHA (American Heart Association)
  • Vice President of Inherited Arrhythmias Committee in CHRS (Chinese Heart Rhythm Society)
  • Fellow of ACC, FACC (American College of Cardiology)
  • Member with Good Standing of European Cardiac Arrhythmia Society (ECAS)

Research Statement

Dr. Hu graduated from Clinical Medicine Department, Medical College of Wuhan University in 1998. She received her M.D. and Ph.D. of Cardiology in the same university in 2003, and became the first one to win Gengshan Award. Then Dr. Hu started her clinical training at Department of Cardiology, Renmin Hospital of Wuhan University as an attending doctor for 2 years. Between 2004 and 2007, she worked as a postdoctoral fellow in Masonic medical research laboratory, Utica, NY. Since 2008, Dr. Dan Hu is the main investigator in Masonic Medical Research Laboratory.

Her field involves translational and clinical cardiology, specifically in the area of electrophysiology and arrhythmia, such as inherited arrhythmogenic cardiac syndromes. She has contributed to discovery of 8 new genes related to Brugada and Early repolarization syndromes, also known as “J Wave Syndromes”. Besides that, she is also experienced on Long/Short QT syndrome, atrial fibrillation, WPW syndrome, sudden cardiac death, and SCD related to myocardial infarction, cardiomyopathy and heart failure, et al. Her expertise also extends to cardiac pharmacology, therapeutics, stem cells, epidemiology, et al.

Her work has led to top peer review papers and highly cited. She has more than 70 publications, 70 abstracts, 3 books, and 70 invited lectures around the world. Now she is serving as Fellow of HRS, Fellow of AHA, Fellow of ACC, and member of several well-known international societies, such as CES, APS. She is also the Vice President of Inherited Arrhythmias Committee in CHRS (Chinese Heart Rhythm Society). Dr. Hu has won several medical awards, including first place of YIA in ACC-NY chapter and Gordon K. Moe YIA. She has been invited to review grant application in USA and Netherland, and serve as reviewer or board member of prominent internationally circulated journals in the field, such as Science – Translational Medicine, Circulation, Heart Rhythm, Plos One, et al. In 2016, she has been selected as image ambassador of fellow and regular member of HRS.